Can I take ivermectin if I am allergic to penicillin?
Ivermectin for Humans is considered to be safe in patients who are allergic to penicillin or who are not allergic to sulfa antibiotics. Ivermectin can cause skin irritations in patients with severe reactions.
It is generally recommended that you avoid all drugs in the immediate penicillin family (amoxicillin, ampicillin, amoxicillin-clavulanate, dicloxacillin, nafcillin, piperacillin-tazobactam as well as certain drugs in the cephalosporin class (a closely related class to penicillins).
Like most drugs, ivermectin can cause an allergic reaction in some people. But this side effect wasn't reported in studies. Symptoms can be mild to serious and can include: skin rash.
Tetracyclines (e.g. doxycycline), quinolones (e.g. ciprofloxacin), macrolides (e.g. clarithromycin), aminoglycosides (e.g. gentamicin) and glycopeptides (e.g. vancomycin) are all unrelated to penicillins and are safe to use in the penicillin allergic patient.
Some of the products that may interact with this drug include: barbiturates (such as phenobarbital, butalbital), benzodiazepines (such as clonazepam, lorazepam), sodium oxybate (GHB), valproic acid.
Approximately 50 percent of people will outgrow a penicillin allergy within five years, and 80 percent will outgrow it within 10 years.
Approximately 10% of all U.S. patients report having an allergic reaction to a penicillin class antibiotic in their past. 10% of the population reports a penicillin allergy but <1% of the whole population is truly allergic. Broad-spectrum antibiotics are often used as an alternative to narrow-spectrum penicillins.
- Coughing, wheezing, and shortness of breath.
- Fever.
- Hives (red bumps on your skin that might be itchy)
- Itchy, watery eyes.
- Itchiness on other parts of your body.
- Runny nose.
- Swelling of your skin, often around your face.
- Tightness in your throat.
Ginger. The scientific community also recognizes ginger as a natural antibiotic. Several studies, including one published in 2017 , have demonstrated ginger's ability to fight many strains of bacteria. Researchers are also exploring ginger's power to combat seasickness and nausea and to lower blood sugar levels.
- dizziness.
- loss of appetite.
- nausea.
- vomiting.
- stomach pain or bloating.
- diarrhea.
- constipation.
- weakness.
Can ivermectin damage your kidneys?
Results showed that administration of ivermectin led to attenuation in kidney function and in activities of the antioxidant enzymes and increase in matrix metalloproteinase-9 activity.
Ivermectin oral tablet is used to treat parasitic infections of your intestinal tract, skin, and eyes.
These experiments demonstrate that ivermectin significantly alters the pharmacokinetics of amoxicillin in rat blood but not in rat brain. Possible mechanisms for this interaction include the blocking by ivermectin of the protein binding of amoxicillin with p-glycoprotein in rat plasma.
Adverse reactions (i.e., pruritus, fever, rash, myalgia, headache) occur commonly during the first 3 days after treatment and appear to be related to the extent of parasitic infection and systemic mobilization and killing of microfilariae.
Zithromax is not a penicillin it is a type of antibiotic called a macrolide. Macrolides kill bacteria by inhibiting protein synthesis and blocking the assembly of the 50S ribosomal subunit, which is a structure in a cell that helps coordinate protein synthesis.
Contraindications / Precautions
Occasionally, systemic ivermectin has been reported to worsen bronchial asthma. Although not extensively studied, due to its extensive hepatic metabolism, ivermectin should be administered with caution in patients with significant hepatic disease.